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Structural Genomics Centers for Infectious Diseases

Publications

Center for Structural Genomics of Infectious Diseases (CSGID)

Benefits of Structural Genomics for Drug Discovery Research. Grabowski M, Chruszcz M, Zimmerman MD, Kirillova O, Minor W. Infect Discord Drug Targets 2009 Oct. 1 [Epub ahead of print]

Structural and molecular mechanism for autoprocessing of MARTX Toxin of Vibrio cholerae at multiple sites. Prochazkova K, Shuvalova LA, Minasov G, Voburka Z, Anderson WF, Satchell KJ J Biol Chem 2009 [Epub ahead of print]

Seattle Structural Genomics Center for Infectious Diseases (SSGCID)

The plug-based nanovolume Microcapillary Protein Crystallization System (MPCS). Gerdts CJ, Elliott M, Lovell S, Mixon MB, Napuli AJ, Staker BL, Nollert P, Stewart L. Acta Crystallogr D Biol Crystallogr. 2008 Nov;64(Pt 11):1116-22. Epub 2008 Oct 18.

Combined protein construct and synthetic gene engineering for heterologous protein expression and crystallization using Gene Composer.
Raymond A, Lovell S, Lorimer D, Walchli J, Mixon M, Wallace E, Thompkins K, Archer K, Burgin A, Stewart L. BMC Biotechnol. 2009 Apr 21;9:37.

Backbone and side chain 1H, 13C, and 15N NMR assignments for the organic hydroperoxide resistance protein (Ohr) from Burkholderia pseudomallei. Buchko GW, Hewitt SN, Napuli AJ, Van Voorhis WC, Myler PJ. Biomol NMR Assign. Epub 2009 May 29. PMID pending.

The Seattle Structural Genomics Center for Infectious Diseases. Myler PJ, Stacy R, Stewart L, Staker B, Van Voorhis WC, Varani G, Buchko GW. Infect Disorders - Drug Targets. 2009 Oct 1. [Epub ahead of print]


Contact

Valentina Di Francesco
Bioinformatics Program Director
Email: vdifrancesco@niaid.nih.gov

Highlight


NIAID Structure of the Month - Nov 2009 

Related Links

UVA Researchers Determine the 3-D Structure of Anthrax Protein (Non-government web site)

CSGID Determines the Structure of 100 Proteins (Non-government web site)

SSGCID Solves 100th Structure, Providing New Information About Infectious Diseases,  (Non-government web site - PDF)



Contact

Valentina Di Francesco
Bioinformatics Program Director
Email: vdifrancesco@niaid.nih.gov

Highlight


NIAID Structure of the Month - Nov 2009 

Related Links

UVA Researchers Determine the 3-D Structure of Anthrax Protein (Non-government web site)

CSGID Determines the Structure of 100 Proteins (Non-government web site)

SSGCID Solves 100th Structure, Providing New Information About Infectious Diseases,  (Non-government web site - PDF)