National Institute of Allergy and Infectious Diseases
NIAID Home Health & Science Research Funding Research News & Events Labs at NIAID About NIAID

VRC Vaccine Research Studies
 Understanding Vaccine Clinical Studies
 How to Volunteer
 Frequently Asked Questions
 Philosophy for Volunteer Recruitment
 Safeguards
 Current Clinical Studies
 Volunteer Profiles
 Archive of VRC Clinical Studies
 Contact Us


VRC Vaccine Research Studies

Current Vaccine Clinical Studies

We are currently enrolling volunteers for a range of studies. If you are interested in volunteering to participate in a clinical trial, please call us at 1-866-833-LIFE (5433) or e-mail us at vaccines@nih.gov.

Studies Open to Accrual

These studies are recruiting.

VRC Clinical Trials Related to Development of Vaccines for Prevention of HIV

VRC 000 (02-I-0127):
Screening Subjects for HIV Vaccine Research Studies

VRC 012 (07-I-0167):
A Phase I Clinical Trial of the Safety and Immunogenicity of an HIV-1 Adenoviral Vector Serotype 35 Vaccine, VRC-HIVADV027-00-VP (rAd35-EnvA): Dose Escalation as a Single Agent and Prime-Boost Schedules with an HIV-1 Adenoviral Vector Serotype 5 Vaccine, VRC-HIVADV038-00-VP (rAd5-EnvA), in Uninfected Adults

HVTN 505 (09-I-0163):
Phase 2, randomized, placebo-controlled trial to evaluate the safety and effect on post-HIV acquisition viremia of a multiclade HIV-1 DNA plasmid vaccine followed by a multiclade HIV-1 recombinant adenoviral vector vaccine in HIV-uninfected, adenovirus type 5 neutralizing antibody negative, circumcised men

VRC Clinical Trials Related to Vaccines for Biodefense and Emerging Pathogens

VRC 300 (03-I-0285):
Screening of Healthy Volunteers for Clinical Trials of Investigational Vaccines to Prevent Infectious Diseases

VRC 309 (10-I-0004)
A Multi-Center, Open-Label, Randomized Phase I Study of an Investigational Influenza DNA Vaccine Followed by 2009/2010 Seasonal Influenza Trivalent Inactivated Vaccine (TIV) Compared to Two Injections of TIV in Adults 45-70 Years 

These studies are not recruiting.

VRC Protocols to Obtain Laboratory Samples for Vaccine and Immunology Research

VRC 200 (03-I-0263):
Apheresis Procedures to Obtain Plasma or Peripheral Blood Mononuclear Cells (PBMCs) for Research Studies

back to top

Learn More about NIH Clinical Studies

  • Understanding National Institutes of Health (NIH) Clinical Trials
  • NIH Healthy Volunteer Program
  • NIH Investigator Resources

  • Guidance regarding HIV anti-retroviral treatment in developing countries
  • Policy on Research Involving Human Subjects

  • Learn More about NIH Clinical Studies

  • Understanding National Institutes of Health (NIH) Clinical Trials
  • NIH Healthy Volunteer Program
  • NIH Investigator Resources

  • Guidance regarding HIV anti-retroviral treatment in developing countries
  • Policy on Research Involving Human Subjects