Biostatistics Research Branch (BRB)

Zonghui Hu

Mathematical Statistician

Interests

Functional data analysis, semiparametric models, measurement error models, longitudinal data analysis, generalized models, biostatistics.

Additional Information

Curriculum Vitae (PDF)

Selected Publications

Selected Statistical Publications:

• Zonghui Hu, Naisyin Wang, Raymond Carroll (2004). Profile-kernel versus backfitting in the partially linear models for longitudinal/clustered data. Biometrika, 91: 251-262.
• Zonghui Hu, Dean Follmann (2007). Statistical methods for active extension trials. Statistics in Medicine, 26:2433-2448.
• Zonghui Hu, Jing Qin, Dean Follmann, Robin Dewar (2008). Nonparametric likelihood approach for assessing the accordance between two measurements and its application to viral load determination with limit of detection. Statistics in Medicine.
• Zonghui Hu, Jing Qin, Dean Follmann (2008). Semiparametric two-sample change-point model. Journal of Royal Statistical Society series C, 57: 589-607.
• Zonghui Hu, Naisyin Wang (2008). Semiparametric mixed-effects model with latent covariate in Colon carcinogenesis study. Statistics and Its Interface, 1: 75-86.
• Erica Brittain, Zonghui Hu (2008). Non-inferiority trial design and analysis with an ordered three-level categorical endpoint. Journal of Biopharmaceutical Statistics, in press.

Selected Medical Publications:

• Alice K Pau, Mary McLaughlin, Zonghui Hu, Michael Polis, Shyamasundaran Kottilil (2006). Predictors for Hematopoietic Growth Factors Use in HIV/HCV Co-Infected Patients Treated with Peginterferon alfa 2b and Ribavirin. AIDS Patient Care and STDs, 9: 612-619.
• Lynne Wu, Shyam Kottilil, Richard Lempicki, Jun Yang, Mary McLaughlin, Zonghui Hu, Chad Koratich, Cathy Rehm, Henry Masur, David E Kleiner, Michael A. Polis (2006). Hepatic histologic response (HR) to combination therapy among HCV/HIV coinfected individuals: Interferon-induces HR independent of Sustained Virologic Response (SVR). AIDS Research and Human Retroviruses, 22: 1091-1098.
• Helene C. Highbarger, Zonghui Hu, Shyam Kottilil, Julia A. Metcalf, Michael A. Polis, M.B. Vasudevachari, H. Clifford Lane, Robin L. Dewar (2007). Comparison of the Abbott 7000 and Bayer 340 systems for measurement of Hepatitis C viral load. Journal of Clinical Microbiology, 45: 2808-2812.
• Daniel L. Suzman, Mary McLaughlin, Zonghui Hu, David E. Kleiner, Brad Wood, Mary Vailati, Ricjard A. Lempicki, JoAnn M. Mican, Anthony Suffredini, Henry Masur, Michael A. Polis, Shyam Kottilil (2008). Identification of novel markers for liver fibrosis in HIV/HCV co-infected individuals using genomics-based approach. AIDS, 22: 1433 – 1439.
• Marta Catalfamo, Michele Di Mascio, Zonghui Hu, Sharat Srinivasula, Vishaka Thaker, Joseph Adelsberger, Adam Rupert, Michael Baseler, Yutaka Tagaya, Gregg Roby, Catherine Rehm, Dean Follmann, and Clifford Lane1 (2008). HIV infection associated immune activation occurs by two distinct pathways that differentially affect CD4 and CD8 T cells. Proceedings of the National Academy of Sciences of the United States of America, in press.

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