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Comparative Medicine
 About CMB
 Veterinarians
 Animal Study Proposals
 Infectious Disease Pathogenesis
  Mouse Necropsy
   Necropsy Sheet
   Instruments and Fixatives
   Necropsy Terms
   1) Starter Kit
   2) First Incision
   3) Lymph Nodes, Mammary Glands
   4) Abdominal Cavity
   5) Urogenital System
   6) Intestines, Stomach, Spleen, Pancreas
   7) Liver 1
   8) Liver 2
   9) Kidneys
   10) Lungs
   11) Heart
   12) Brain
   References
  Veterinary Pathology


Comparative Medicine Branch

Mouse Necropsy

Step 11: The Heart

  1. Superior vena cavaHeart illustration
  2. Right atrium
  3. Right ventricle
  4. Left ventricle
  5. Inferior vena cava
  6. Aorta
  7. Pulmonary vein
  8. Left atrium
  9. Pulmonary artery
  10. Aortic arch
  11. Left superior vena cava

 

 

 

 

 

 

 

For the most part, there will be no need to separate the heart from the lungs, but you may need to examine the heart. If the heart is touching or is almost touching the diaphragm at the time  the sternum is removed, it is a sign that the heart is enlarged. As the diaphragm is punctured, the pressure in the thoracic cavity will change, causing the heart to retract, so it is a good time to make this observation. As in humans who don't get a great deal of exercise, are obese, or are getting old, the heart of an old, obese, or sedentary mouse will be enlarged. Heart enlargement and heart lesions are typical in older animals. Also, don't be alarmed if the heart is still beating. Because of electric currents running through the body after death, some movement of the heart and various other muscles will continue to occur after euthanasia.

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