Comparative Medicine Branch

Veterinary Pathology

Pathology and Biology of Genetically Engineered Mice

From The Jackson Laboratory

Mouse Mutant Resources

• Mouse Models Resources
• NCI Mouse Models of Human Cancer Respository
• World Directory of Knockout Mice
• The Jackson Laboratory Induced Mutants Resource

Mouse Pathology

• NCI MMHCC Mouse Models Tumor Classifications
• Lymphoid - Bethesda proposals for classification of lymphoid neoplasms in mice
• Myeloid - Bethesda proposals for classification of nonlymphoid hematopoietic neoplasms in mice
• Mammary - The mammary pathology of genetically engineered mice: the consensus report and recommendations from the Annapolis meeting
• Brain - Neuropathology of genetically engineered mice: consensus report and recommendations from an international forum
• Intestine - Pathology of mouse models of intestinal cancer: consensus report and recommendations
• Tumors in 129, C57BL and 129 x C57BL Mice
• Complete aging study of B6;129 wild type mice
• The Jackson Laboratory Mouse Tumor Biology Database

Mammary Tumors

• Mouse Models of Breast Cancer - The Cardiff CD-ROM

Books on Mouse Biology and Pathology

Non-federal Web site links to order the books:

• Mouse Genetics Online (Silver)
• Mouse Models of Human Cancers (EC Holland, editor)
• International Classification of Rodent Tumours. The Mouse
• Systematic Evaluation of the Mouse Eye (Smith, John, Nishina, Sundberg)
• Handbook of Mouse Mutations with Skin and Hair Abnormalities (Sundberg)
• Atlas of Mouse Hematopathology - with color figures, by Fredrickson and Harris
• Pathology of Genetically Engineered Mice, 500 color figures, edited by JM Ward (NCI), J Mahler (NIEHS), RR Maronpot (NIEHS), JP Sundberg (The Jackson Laboratory) and R Frederickson (NCI)
• Pathology of The Mouse -with over 1000 figures, edited by RR Maronpot (NIEHS)
• Systemic Approach to Evaluation of Mouse Mutations, edited by JP Sundberg and D Boggess (The Jackson Laboratory)
• The Clinical Chemistry of Laboratory Animals - edited by WF Loeb and F Quimby
• Behavioral Phenotyping of Transgenic and Knockout Mice - by J Crawley (NIH)
• Pathology of Laboratory Rodents and Rabbits, Second Edition, 2001 - by Percy and Barthold
• The Laboratory Mouse (Suckow, Hanneman, Brayton)
• Handbook of Toxicologic Pathology, Second Edition
• The NIEHS CDROM On Pathology of GEM
• The NIEHS CDROM of Mouse Liver Lesions

Mouse Phenotyping

The Necropsy

• The NIH Virtual Mouse Necropsy
• The Euro Cavelli Mouse Necropsy
• Columbia U Mouse Necropsy Procedures
• Necropsy Guide : Rodents and the Rabbit (Feldman & Seely)
• Tissue Trimming Procedures

Pathology

• Evaluating Mutant Mice: Anatomic Pathology. Brayton et al (Veterinary Pathology 38:1-19, 2000)
• SHIRPA
• Columbia U Mouse Protocols
• The Jackson Laboratory Mouse Phenome Database
• The Jackson Laboratory Mouse Tumor Biology Database
• Virtual Microscopy
• Human Whole Slide Scanning - The Virtual Slidebox of Histopathology
• Human and Mouse Hematopoietic Tumor Slide Sets

Web Resources for Mouse Genetics, Biology and Pathology

• The Mouse Genome
• The Trans-NIH Mouse Initiative
• Nomenclature of Mouse Strains

Mouse Models of Human Diseases

• NIH Mouse Models of Heart, Lung and Blood Diseases
• NCI Mouse Models of Human Cancer

Embryos

• Comparative Placentation
• Caltech Mouse Atlas
• The Mouse Atlas and Gene Expression Database - with CD ROM - from Edinburgh
• The Virtual Embryo
• Dr. Wasserman's Developmental Biology Page

Mouse Embryo Books

Non-federal Web site links to order the books:

• Mouse Development: Patterning, Morphogenesis and Organogenesis, by Rossant, Tam and Tam, 2002
• The Anatomical Basis of Mouse Development, by Bard and Kaufman, 1999
• Atlas of Mouse Development, by M. Kaufman, 1992

Mouse Placenta - Reviews

• Placental development - by J. Rossant and JC Cross
• Gestational mortality in genetically-engineered mice: evaluating the extra-embryonic placenta and membranes, by JM Ward and DE Devor-Henneman in Pathology of Genetically Engineered Mice

Veterinary Pathology Image Databases

• Frontiers in Bioscience Gene KO Database
• Mouse Brain Library
• Cornell University Veterinary Neuropathology Web Atlas
• Cornell University John King's Show and Tell
• Deltagen Mouse Histology Atlas

Consultation in Targeted Mutant Mouse Biology and Pathology

Do you have a new mutant mouse and need advice to help evaluate its phenotype? E-mail us.

back to top