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Infectious Disease Pathogenesis
 Mouse Necropsy
 Veterinary Pathology


Comparative Medicine Branch

Mouse Antigens 

CD3: Lymph Node, Spleen,Thymus

Lymph Node

Mouse lymph node with many CD3+ T-cells in the paracortex, and the cortex.
Mouse lymph node with many CD3+ T-cells in the paracortex, and the cortex.Photograph.

Spleen

Mouse splenic CD3 expression in PALS of white pulp and in scattered cells in red pulp.
Mouse splenic CD3 expression in PALS of white pulp and in scattered cells in red pulp.Photograph.

Mouse spleen -CD3 expression in T-cells in the PALS/.
Mouse spleen -CD3 expression in T-cells in the PALS. Photograph.

Mouse spleen showing expression of CD3 in the PALS and red pulp.
Mouse spleen showing expression of CD3 in the PALS and red pulp.Photograph.

Mouse spleen -CD3 in strongly positive T-cells in the PALS and less in other areas of white pulp and in red pulp.
Mouse spleen -CD3 in strongly positive T-cells in the PALS and less in other areas of white pulp and in red pulp.

Mouse splenic -CD3 strongly positive T-cells with cell membrane expression.
Mouse splenic -CD3 strongly positive T-cells with cell membrane expression.

Thymus

Mouse thymus - CD-3 low magnification showing many + cells in cortex and less in medulla.
Mouse thymus - CD-3 low magnification showing many + cells in cortex and less in medulla. Photograph.

Mouse thymus - CD-3 low magnification showing many + cells in cortex and less in medulla.
Mouse thymus - CD-3 low magnification showing many + cells in cortex and less in medulla. Photograph.

Mouse thymus - CD-3 expression 48 hours after dexamethazone showing severe loss of CD3+ T-cells in the thymus.
Mouse thymus - CD-3 expression 48 hours after dexamethazone showing severe loss of CD3+ T-cells in the thymus.Photograph.

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    See Also

  • Division of Intramural Research (DIR)
  • Training Resources