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Infectious Disease Pathogenesis
 Mouse Necropsy
 Veterinary Pathology


Comparative Medicine Branch

Mouse Antigens

CD45R: Lymph Node, Peyer's Patch, Spleen

Lymph Node

Mouse mesenteric lymph node -CD45R (B220)+ cortical B-cell follicles and medullary cords.
Mouse mesenteric lymph node -CD45R (B220)+ cortical B-cell follicles and medullary cords.Photograph.

Peyer's Patch

Mouse CD45R early follicular lymphoma in Peyer’s patch of the small intestine showing disruption of normal CD45R expression pattern and enlargement of the patch.
Mouse CD45R early follicular lymphoma in Peyer’s patch of the small intestine showing disruption of normal CD45R expression pattern and enlargement of the patch.Photograph.

Spleen

Mouse splenic CD45R in several white pulp areas, in follicles and marginal zone.
Mouse splenic CD45R in several white pulp areas, in follicles and marginal zone.Photograph.

Mouse splenic CD45R (B220) shows a white pulp area with many positive B-cells in a follicle, marginal zone and red pulp.
Mouse splenic CD45R (B220) shows a white pulp area with many positive B-cells in a follicle, marginal zone and red pulp.Photograph.

Mouse spleen with CD45R expression on cell membranes of B-cell follicular lymphoma cells in various stages of differentiation.
Mouse spleen with CD45R expression on cell membranes of B-cell follicular lymphoma cells in various stages of differentiation. Photograph.

Mouse spleen - CD45R in early nodular follicular lymphoma in one white pulp area, showing loss of normal white pulp expression pattern of CD45R.
Mouse spleen - CD45R in early nodular follicular lymphoma in one white pulp area, showing loss of normal white pulp expression pattern of CD45R.Photograph.

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    See Also

  • Division of Intramural Research (DIR)
  • Training Resources