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Infectious Disease Pathogenesis
 Mouse Necropsy
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Comparative Medicine Branch

Rat Antigens

Ox-8: Liver, Lung, Lymph Node, Peyer's Patch, Small Intestine, Spleen, Thymus

Liver

Rat liver- OX-8+ tumor cell membranes in liver sinusoids and blood vessels in LGL leukemia in a F344 rat.
Rat liver- OX-8+ tumor cell membranes in liver sinusoids and blood vessels in LGL leukemia in a F344 rat. Photograph.

Rat liver showing OX-8 expression on cell membranes on LGL leukemia tumor cells.
Rat liver showing OX-8 expression on cell membranes on LGL leukemia tumor cells. Photograph. 

Lung

Rat LGL leukemia showing OX-8 expression in many tumor cells in alveolar capillaries in the lung.
Rat LGL leukemia showing OX-8 expression in many tumor cells in alveolar capillaries in the lung. Photograph. 

Lymph Node

Rat OX-8 (CD8) expressed in many T-cells in the paracortex of the lymph node.
Rat OX-8 (CD8) expressed in many T-cells in the paracortex of the lymph node.  Photograph. 

Peyer's Patch

Rat OX-8 (CD8) expression in interfollcular cells of small intestinal Peyer’s patch.
Rat OX-8 (CD8) expression in interfollcular cells of small intestinal Peyer’s patch. Photograph. 

Small Intestine

Rat small intestine showing expression of OX-8 in intra-epithelial lymphocytes.
Rat small intestine showing expression of OX-8 in intra-epithelial lymphocytes. Photograph. 

Spleen

Rat spleen OX8 (CD8) expression in the PALS and red pulp T-cells.
Rat spleen OX8 (CD8) expression in the PALS and red pulp T-cells. Photograph.

Thymus

Rat thymic OX-8 (CD8) is seen diffusely expressed cortical lymphocytes with much less in the medulla.
Rat thymic OX-8 (CD8) is seen diffusely expressed cortical lymphocytes with much less in the medulla. Photograph.

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  • Division of Intramural Research (DIR)
  • Training Resources