Introduction
To build upon the objectives of the NIAID genomics programs and address the Institute’s need to further expand the knowledge of the proteome, in September 2007, NIAID launched a 5-year initiative to establish large-scale NIAID Structural Genomics Centers for Infectious Diseases that will apply state-of-the-art, high-throughput structural biology technologies to experimentally characterize the three-dimensional atomic structure of targeted proteins from pathogens in the NIAID Category A – C priority lists and organisms causing emerging and re-emerging infectious diseases.
The primary focus of the Structural Genomics Centers for Infectious Diseases are pathogen targets that are expected to have an important biological role and a potential impact on biomedical research, such as proteins involved in pathogenesis, proteins involved in antimicrobial/drug resistance, complexes with natural substrates, cofactors, receptors, and drug candidates.
The Centers accept requests for pathogen protein targets by external investigators, the National Institutes of Health, and other government agencies. To submit a request, please contact the Centers directly by following the links provided below.
Original Solicitation
NIAID contract solicitation (PDF)
Awards
Northwestern University
University of Chicago; J. Craig Venter Institute; University College of London; University of Texas Southwestern Medical Center in Dallas; University of Toronto; University of Virginia; Washington University School of Medicine.
Principal Investigator: Dr. Wayne Anderson
Web site: Center for Structural Genomics of Infectious Diseases (CSGID) (Non-government link)
Targets Request Process: Instructions on how to submit protein target requests to CSGID can be found here.
Seattle Biomedical Research Institute
DeCODE Biostructures; University of Washington; Battelle Memorial Institute
Principal Investigator: Dr. Peter Myler
Web site: Seattle Structural Genomics Center for Infectious Diseases (SSGCID) (Non-government link)
Targets Request Process: Instructions on how to submit protein target requests to SSGCID can be found here.
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