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Conformational Epitopes
- Antigens are protein molecules formed by linking amino acids together to assume a particular shape that immune cells can recognize.
- Scientists can link amino acids together to try to form a protein molecule, but it is difficult to produce a protein molecule that assumes the proper shape (conformation).
- Researchers are designing new synthetic forms of the HIV envelope molecule that will assume the same shape as the molecule of the wild virus (oligomeric gp120).
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