Symptoms
Not all people with ALPS will have all of its symptoms; some people have only a few. Signs of ALPS that are seen most often include the following:
- Enlarged spleen
- Enlarged lymph nodes, especially in the neck and underarms
- Enlarged liver
- Skin rashes
- Thombocytopenia (low platelet count), which can cause bruising, nose bleeds, and may pose a risk for hemorrhage (excessive bleeding); little red spots called petechiae (pet-eek'-ia) may also show up on the skin when platelets are low
- Anemia (low red blood cell count), which can cause increased fatigue or pallor
- Neutropenia (low neutrophil count), which can create a risk for bacterial infections