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Biodefense

NIAID Small Business Biodefense Program

FY 2004 Awards

InstitutionPI NameTitle
Allied Innovative Systems, LLCSimon BystryakRapid detection of food borne pathogenic bacteria
Apath, LLCPaul OlivoMolecular tools for Bunyavirus antiviral screening
Apath, LLCPaul OlivioReplicon-based screening for inhibitors of alphaviruses
Avanir PharmaceuticalsAngray KangHuman Antibodies for Exposure/Protection from Anthrax
Biorexis Pharmaceutical CorporationJames BallanceA Broad, Long Acting Inhibitor of Botulinum Neurotoxin
Bioscale, Inc. Alexis Sauer-BudgePathogen Biosensor Array for Syndrome-Based Diagnostics
Cellerant Therapeutics, Inc.Timothy FongExpansion of HSC for rescue in biodefense applications
Cellex, Inc. Xing-Xiang LingA Rapid, Sensitive and Fully Automated Y. pestis Test
Core MicrosolutionsChang-Jin KimIn toto Handheld Bioagent Detector by Digital Fluidics
Dakota Technologies, Inc. Kirk HartelMultiplex DNA Detection Without Fluorophore Labeling
Delsite Biotechnologies, Inc. Yawei NiAn in-situ gelling nasal vaccine delivery platform
EIC Laboratories, Inc.Michael WilsonRapid Immunoassays for Detecting Pathogenic Bacteria
Emetagen, LLC Robert GoodmanDiscovery of Anti-Bioweapon Agents in BAC Librarie
Epivac, Inc. Anne De GrootA Genome-Derived, Epitope-Driven Tularemia Vaccine
Eragen Biosciences, Inc. James PrudentRapid Detection of Agents that Cause Respiratory Disease
Eragen Biosciences, Inc. James PrudentRapid Turn-arround Multiplex Testing: Bioweapon Agents
Genomics USA, Inc.Rahul MitraPopulation-scale HLA typing for home land defense
Hawaii Biotech, Inc.Axel LehrerRecombinant Subunit Vaccine for Tick-Borne Encephalitis
Hawaii Biotech, Inc. Alan McClellandInhibitors of Anthrax Lethal Factor Metalloproteinase
Hemocleanse, Inc.Stephen AshPheresis Treatment of Bioterrorism-Induced Sepsis
Hepadnavirus Testing, Inc.Patricia MarionNew broad-spectrum antivirals: target bunyaviruses
Immport Therapeutics, Inc.Philip Felgner Vaccinia Proteome Affinity Reagents From Phage Display
Indevr, LLCKathy RowlenAdvanced Detection Technologies for Biochips
Innoject, Inc.Richard GillespieInfluenza Self-Administration Vaccine System
Innovative Biologics, Inc.Vladmimir KarginovSmall Molecule Blockers of B. anthracis Toxin
Integral MolecularEva HarrisDengue Reporter Virus Particle Neutralization Assay
Iogenetics, LLCMichael ImbodenAntibody-Biocide Fusions to Control Cryptosporidium
L2 Diagnostics, LLCRaymond KoskiAntibody Prophylaxis and Therapy of Flavivirus Infection
Ligocyte PharmaceuticalsAiyappa PalecandaAnthrax Vaccine Formulations Combining PA/Spore Epitopes
Lpath Therapeutics, Inc.Roger SabbadiniTherapeutic Approach to Sulfur Mustard Exposure
Macrogenics, Inc.Stacy FergusonDevelopment of Novel Brucella Vaccine Candidates
Microbiotix, Inc.Donald MoirDiscovery of B. pseudomallei Therapeutics for Biodefense
Molecular Express, Inc.William ErnstUniversal Influenza Matrix 2 Subunit Vaccine
Molecular Therapeutics, Inc.Prasad SunkaraHexa-D-Arg: A Furin Inhibitor for Anthrax Biodefense
Molsoft, LLCMaxim TotrovRational Design of Inhibitors of Yersinia pestis EF-Tu
Neurobiotex, Inc.Christopher FredericksonHigh-Speed Microfluidic Sorting of Biohazardous Cells
Neurome, IncDavid LoAdjuvants for Mucosal Immunity
Neurome, IncDavid LoFAE specific receptors for targeted vaccine delivery
Nexbio, IncFang FangIdentifying Broad-Spectrum Influenza Virus Inhibitors
Nexbio, IncFang FangNovel Therapeutics for Pandemic and Epidemic Flu
Nexbio, Inc.Mang YuBroad-Spectrum Therapeutics for Influenza
NomadicsJean ClarkePolymer-Based Yersinia Pestis Point-of-Case Diagnostics
Novobiotic PharmaceuticalsLosee LingDeveloping Novel Antibiotics Against Yersinia pestis
Origen TherapeuticsPhilip LeightonHuman immunotherapeutics for Biodefense Applications
Paratek PharmaceuticalsMichael AlekshunNovel Therapeutics for Biodefense
Polymedix, Inc.Richard ScottBiomimetic antimicrobials for biowarfare pathogens
Protein Potential, LLCKim Lee SimA Tetravalent Dengue Recombinanat Protein Vaccine
Redstorm Scientific, Inc.Steven WhittenAntiviral Agents directed at West Nile Virus
Sensor Technologies, Inc. David WolfImproved Pathogen Detection by Fluorescence Correlation
SeralogixKenneth Drake BWA Host-Pathogen Innate Immune S/W Analysis Tools
Siga Technologies, Inc.Dennis HrubyAntiviral Drugs for Category A Arenavirus
Siga Technologies, Inc.Dennis HrubySmall Molecule Inhibitors of Smallpox Virus Replication
Techlab, Inc. David LyerlyNew Diagnostics for Amebiasis
Transtech Pharma, Inc.Murty ArimilliNovel Orthopox Small Molecule Anti-Virals
TSRL, Inc.John HilfingerImproving Absorption and Targeting of Antiviral Drugs
Vaccinex, Inc. Ernest SmithHuman Monoclonal Antibodies for Bioterrorism Defense
Vaxinnate CorporationThomas PowellDiscovery of Novel TLR Ligands with Adjuvant Properties

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