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Biodefense

Biodefense and Emerging Infectious Diseases Research Opportunities
PA03-080 — Exploratory/Developmental Grants (R21s)

FY 2006 Awards

InstitutionPI NameTitle
American Type Culture CollectionTimothy LilburnAccelerating metabolic discovery using characterization data
Children's Hospital, BostonSimon DoveVirulence gene control in Francisella tularensis
Children's Hospital, BostonSimon DoveThe alpha subunits of Francisella tularensis RNA polymerase
Children's Research InstituteMark PeeplesGeneration of a Single-Cycle Virus to Study the Pathogenesis of Nipah Virus
Columbia University Health SciencesIla SinghNew approach to study West Nile virus fusion into cells
Emory UniversityChinglai YangNovel DNA/VLP Vaccines Against Influenza
Kansas State UniversityRollie ClemApoptosis as an anti-viral response in mosquito midgut
Louisiana State University A&M College, Baton RougeKevin MacalusoComparative rickettsial protein profiles during tick infection
Louisiana State University Health Sciences Center, ShreveportJames CardelliIFN-gamma Induced Macrophage GTPases in Brucella Killing
Louisiana State University Health Sciences Center, ShreveportKatherine RymanInnate immune evasion and/or antagonism by eastern equine encephalitis virus
Massachusetts General HospitalMarcia GoldbergShiga toxin-encoding phage adsorption and toxin release
New England Medical Center HospitalsRoberta O'ConnorRole of Cryptosporidium Mucins in Host-parasite interactions
New England Medical Center HospitalsHonorine WardInnate Immune Recognition of Cryptosporidium parvum
New York University School of MedicineKam-Meng Tchou-WongNew Therapeutic Approach for Ricin-Induced Lung Injury
Northern Arizona UniversityFernando MonroyToxoplasma gondii: neuro-intestinal interactions
Rutgers, the State University of New Jersey, BrunswickNilgun TumerIdentification of the ribosomal target of Shiga-like toxins
Scripps Research InstituteStefan KunzCellular receptors for pathogenic New World arenaviruses
Sloan-Kettering Institute for Cancer ResearchRonald DematteoNatural Killer Dendritic Cells in Listeria Infection
Southern Research InstituteDiana NoahInvestigation of influenza virulence mediated by the NS1A protein
State University of New York, Stony BrookNancy ReichRole of ISG54 in Response to Viral Infection
Texas Agricultural Experiment StationStanley RiderCryptosporidium parvum Histone Deacetylases
Thomas Jefferson UniversityJames McGettiganSecond Generation Rabies Vaccines
Torrey Pines Institute for Molecular StudiesSally SarawarInteraction between influenza virus and H. influenzae
Tufts University, BostonJeffrey GriffithsTransmission and the respiratory tract in cryptosporidiosis
Tufts University, BostonMatthew WaldorIntestinal colonization of Enterohemorrhagic E. coli
University of Medicine & Dentistry of New Jersey, New Jersey Medical SchoolMukund ModakStudies of DNA Pol I and Pol E2 of M. tuberculosis
University of California, Los AngelesRobert LehrerRetrocyclin reinforcement of pulmonary defenses against viral aerosols
University of Connecticut School of Medicine and DentistryLinda CauleyLong Term Effects of Influenza Virus on T Cell Migration
University of FloridaLei ZhouComparative Analysis of Cell Death Regulation in Mosquitoes
University of GeorgiaMark SchellExtracellular Proteins in Virulence of B. (pseudo)mallei
University of Illinois at ChicagoPavel PetukhovSmall molecule inhibitors pantothenate synthesis against M. tuberculosis
University of IowaWendy MauryFilovirus/cellular receptor interactions
University of Maryland, College Park CampusDaniel PerezAvian Influenza Vaccines for Pandemic Preparedness
University of Maryland, College Park CampusXioping ZhuImmunogenicity of Subunit Vaccine Delivered by FcRn
University of Michigan at Ann ArborGary LukerImaging Vaccina Viral-Host Pathogenesis
University of New Mexico, AlbuquerqueGraham TimminsAntimycobacterial NO from KatG Activation of Isoniazid
University of Pittsburgh at PittsburghSaleem KhanFunctions of the PcrA Helicase in Bacillus anthracis
University of RochesterMartin PavelkaIdentification of secreted proteins important for tulremia pathogenesis
University of RochesterAndrea SantManipulation of immunodominance to promote heterosubtypic immunity to Influenza
University of SheffieldAndrew HeathNovel Protein Adjuvant
University of South AlabamaJonathon AudiaElucidating the Rickettsia prowazekii EnvZ/OmpR Regulon
University of Texas, AustinKrishnendu RoyNovel Adjuvant Formulations for Genetic Vaccines
University of Texas Health Sciences Center, HoustonBlanca RestrepoRapid characterization of mycobacteria and drug resistance in paucibacillary TB
University of Wisconsin, MadisonGary SplitterGenomic Island-5 in Brucella Pathogenesis
Vanderbilt UniversityMark McClainInhibitors to Clostridium perfrigens epsilon toxin
Virginia Commonwealth UniversityGail ChristieHelper Phage Mobilization of Staphylococcal Enterotoxin Genes
Wayne State UniversityPaul RobertsAvian Influenza Virus Vaccines Bearing Immunomodulators
West Virginia UniversityChristian StehlikViral PYRIN-only proteins as suppressors of the host immune response
Yale UniversityJeffrey KahnThe Role of a Novel Coronavirus In Kawasaki Disease
Yale UniversityRuth MontgomeryMechanism of Vector Saliva Inhibition of Innate Immunity
Yeshiva UniversityLouis WeissA Therapeutic Target for Microsporidiosis

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