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Biodefense

NIAID Small Business Biodefense Program—FY2007 Awards

Institution PI Name Title
Akonni Biosystems, Inc. Chandler, Darrell P. Diagnostic Protein Array for Respiratory Infections
Akonni Biosystems, Inc. Chandler, Darrell P. Integrated, On-Chip Rt-Mme-Pcr for Influenza Diagnostics; Phase 1 = Sample Prepar
Aureogen Biosciences, Inc. Elhammer, Ake P. A Bacitracin Derivative for Systemic Use
Bcr Diagnostics Rotman, Boris Engineered Spores as Fluorogenic Biological Indicators for Sterility Testing
Biotex, Inc. Jackson, George W. Rapid Microbial Identification by Maldi-Tof Mass Spectrometry of Ribosomal Rna
Cellex, Inc. Li, Xing-Xiang An Affinity Column for Influenza Virus Vaccine Manufacturing
Centrose, LLC Hutchinson, Charles R. Novel Macrolides as Anti-Infective Drugs
Emetagen, LLC Urbach, Ena Antibiotics from Soil DNA Clone Libraries: Selection of Anti-Mrsa Lead Compounds
Epivax, Inc. De Groot, Anne Searls Optimization of a Multivalent Tuberculosis Vaccine
Id Fish Technology, Inc. Shah, Jyotsna S. Tb-Fish Assay for Direct Detection Of M. Tuberculosis in Unprocessed Sputum
Idx Labs, LLC Houpt, Eric R. Targeted DNA Extraction for Tuberculosis Pcr from Sputum
Immunotope, Inc. Philip, Ramila Defining T Cell Epitopes in Dengue Virus Infection
Inbios International, Inc. Houghton, Raymond Rapid Antigen Detection Test for Dengue Infection
Innovative Biologics, Inc. Karginov, Vladimir A. Small Molecule Inhibitors of C. Perfringens Epsilon-Toxin
Integral Molecular Harris, Eva Dengue Reporter Virus Neutralization Assay for Clinical Studies
Investigen, Inc. Koshinsky, Heather A. Rapid, Easy Nucleic Acid-Based Detection of Pulmonary Tuberculosis
Inviragen, LLC Stinchcomb, Dan T. Mva-Based Vaccines against Highly Pathogenic Avian Influenza
Lancell, LLC Cowing, Carol O. Topical Adjuvants to Enhance the Efficacy of Influenza Vaccines
Litron Laboratories, Ltd. Dertinger, Stephen D. High-Throughput Radiation Biodosimetry
Mapp Biopharmaceutical, Inc. Zeitlin, Larry A Monoclonal Antibody Immunoprotectant for Ebola Virus
Medivas, LLC Defife, Kristin Marie Immunogenicity Testing of a Fully Synthetic Subunit Vaccine against Influenza
Mercia Pharma, Inc. Blackburn, Peter Adjuvanted Influenza Vaccine
Microbiotix, Inc. Lory, Stephen Tlr5 Antagonists for Infectious Disease Therapy
Microbiotix, Inc. Peet, Norton P. Quinoline-Based Inhibitors of Botulinum Neurotoxin A
Microbiotix, Inc. Peet, Norton P. Inhibition of Ebola Virus Infection with Cathepsin L Inhibitors
Najit Technologies, Inc. Fitchen, John Rapid Diagnosis of Monkeypox and Smallpox Infections
Nature Technology Corporation Williams, James Rapid Deployment DNA Vaccine for Pandemic Influenza
Nirvana Pharmaceuticals, Inc. Lindsey, Jonathan Sidney Stable Cationic Bacteriochlorins for Antimicrobial Photodynamic Therapy
Novadigm Therapeutics, Inc. Yeaman, Michael R. Novel Context-Activated Protide Anti-Infectives
Novobiotic Pharmaceuticals, LLC Moore, Charles Michael Isolating Novel Fungi for Antibiotic Discovery
Panthera Biopharma, LLC Lehrer, Axel T. Development of a Recombinant Subunit Ebola Vaccine
Panthera Biopharma, LLC Johnson, Alan Thomas Inhibitors of Anthrax Lethal Factor Metalloproteinase
Rocky Mountain Biosystems, Inc. Marchitto, Kevin Self-Administered Vaccination Electromechanical Device for Influenza
Seralogix Drake, Kenneth L. Bwa Host-Pathogen Innate Immune S/W Analysis Tools
Sibtech, Inc. Backer, Marina V. Targeted Delivery of Anthrax Inhibitors
Siga Technologies, Inc. Hruby, Dennis E. Enhancing the Immune Response to Antigens Delivered by the Bacterial Vector, Stre
Siga Technologies, Inc. Grosenbach, Douglas W. St-246 Treatment of Smallpox Vaccine-Related Adverse Events in Murine Models
Soymeds, Inc. Piller, Kenneth J. A Novel Therapy for Staphyloccocal Enterotoxin B Poisoning
Syntiron, LLC Herron-Olson, Lisa Yersinia Membrane Proteins as Vaccine Candidates
Techlab, Inc. Carman, Robert James Mucin-Degrading Microflora for Prophylactic Antibiotics
Tsrl, Inc. Hilfinger, John M. Vidarabine Prodrugs as Anti-Pox Virus Agents
Tsrl, Inc. Hilfinger, John M. Improving Absorption and Targeting of Antiviral Drugs
Vaxinnate Corporation Mcdonald, William F. Development of a Tetravalent Dengue Vaccine That Links Innate and Adaptive Immuni
Vectorlogics, Inc. Hedley, Susan J. Development of Shielded Adenovirus Vector as a Vaccine Strategy for Anthrax
Virogenomics, Inc. Heffron, Fred L. Genetically Defined Attenuated Living Vaccine for Francisella
Vital Probes, Inc. Delvecchio, Vito G. Development of a Bacterial Ghost DNA Vaccine for Influenza Using Antibody Epitope
West Coast Biologicals, Inc. Tucker, Sean N. Enhanced Oral Vaccine Delivery Vehicle

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